Propylene Glycol 50% – USP Grade (C3H8O2)

Product Identifier

Propylene Glycol 50% – USP Grade (C3H8O2)

Grade

USP Grade

Concentration

50%

CAS Number

57-55-6

Molecular Weight

76.09 g/mol

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Recommended Use

Ready-to-use propylene glycol and water blend (50% PG): heat-transfer fluid and antifreeze for closed-loop systems; humectant and solvent carrier.

Restrictions on Use

No restrictions identified beyond the conditions of safe use in Sections 7 and 8.

Signal Word

Not applicable

Hazard Statements

Not classified as hazardous under GHS based on available data.

Precautionary Statements

No specific GHS precautionary statements required.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with water. Get medical attention if irritation develops or persists.

Skin

Wash with soap and water. Get medical attention if irritation develops.

Inhalation

Move to fresh air if discomfort occurs.

Ingestion

Rinse mouth with water. Get medical attention if you feel unwell.

Most Important Symptoms and Effects

• No specific symptoms are expected from the hazards identified in Section 2.

Immediate Medical Attention and Special Treatment

• Treat symptomatically. Get medical attention if symptoms develop or persist.

Suitable Extinguishing Media

Use water spray, alcohol-resistant foam, dry chemical, or CO2. Use measures appropriate to local circumstances.

Unsuitable Extinguishing Media

Do not use a solid water stream as it may scatter and spread fire.

Specific Hazards Arising from the Chemical

Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Carbon monoxide and carbon dioxide on combustion; aldehydes, alcohols, ethers and organic acids on oxidation at high temperature.

Personal Precautions

Wear safety glasses and gloves for cleanup. Spills can make floors slippery.

Environmental Precautions

Avoid releasing large quantities to drains or waterways.

Containment & Cleanup

Absorb or wipe up, then rinse the area with water. Dispose of according to local regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area. Keep away from incompatible materials (see Section 10). Keep containers tightly closed.

Specific Storage Precautions

Keep tightly closed (hygroscopic) in a cool, dry place away from oxidizers. Stainless steel, carbon steel, polyethylene or polypropylene containers.

Occupational Exposure Limits

No established occupational exposure limits.

Engineering Controls

General ventilation is normally adequate.

Eye/Face Protection

Safety glasses are recommended.

Skin Protection

Gloves are recommended for prolonged or repeated contact.

Respiratory Protection

Not normally required.

Appearance

Clear, colorless to pale liquid

Odor

Mild, characteristic

Odor Threshold

No data available

pH

Essentially neutral (unbuffered blend)

Melting Point / Freezing Point

-34 °C (freeze / crystallization onset)

Boiling Point

~106 °C

Flash Point

Not flammable (aqueous solution)

Evaporation Rate

No data available

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

No data available

Vapor Pressure

No data available

Vapor Density

No data available

Relative Density

1.046 (20 °C)

Solubility

Miscible with water

Partition Coefficient (n-octanol/water)

No data available

Auto-ignition Temperature

No data available

Decomposition Temperature

No data available

Viscosity

No data available

Particle Characteristics

Not applicable

Color

10 APHA (maximum)

Density

1.046 g/mL at 20 °C

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Contact with strong oxidizers; prolonged heating in air (slow oxidation to aldehydes and acids). Hygroscopic: absorbs moisture from air.

Incompatible Materials

Strong oxidizing agents; strong acids; strong bases.

Hazardous Decomposition Products

Carbon monoxide and carbon dioxide on combustion; aldehydes, alcohols, ethers and organic acids on oxidation at high temperature.

See Section 2 for GHS hazard classification.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• No specific symptoms are expected from the hazards identified in Section 2.

Delayed and Chronic Effects

• No delayed or chronic effects identified beyond the classification in Section 2.

Numerical Measures of Toxicity

No data available

Carcinogen Classification

Ecotoxicity

Algae ErC50: 19000 mg/L (96 h, Selenastrum capricornutum (14-d growth rate)); Daphnia EC50: 43500 mg/L (48 h, Daphnia magna (static))

Persistence & Degradability

Not persistent; low soil/sediment adsorption, not expected to volatilize

Bioaccumulative Potential

log Kow −0.92

Mobility in Soil

Very high mobility in soil (estimated Koc ≈ 1)

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

Not regulated for transport under US DOT 49 CFR Subchapter C, IMDG, or IATA DGR.

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.

Revision Date

2026-10-13

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.