Corrosion-inhibited ethylene glycol (ACS grade): laboratory heat-transfer baths and coolant formulation where a phosphate-buffered glycol is required.
Restrictions on Use
Not for food, drug or cosmetic use. Toxic if swallowed in quantity (it tastes sweet): keep away from children and pets, and do not store in food or drink containers.
Section 2
Hazard Identification
Irritant / harmfulHealth hazard
Classification
Acute toxicity (oral), Category 4
Specific target organ toxicity, repeated exposure, Category 2
Signal Word
Warning
Hazard Statements
H302Harmful if swallowed
H373May cause damage to organs through prolonged or repeated exposure
Precautionary Statements
P260Do not breathe dust, fume, gas, mist, vapors or spray.
P264Wash hands and face thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell.
P314Get medical advice or attention if you feel unwell.
P330Rinse mouth.
P501Dispose of contents and container in accordance with local, regional, national, and international regulations.
Classification, hazard (H) and precautionary (P) statements and pictograms per OSHA HCS 2024 (29 CFR 1910.1200, Appendices A–C), aligned with GHS Rev. 7.
Section 3
Composition / Information on Ingredients
Composition and information on ingredients
Component
CAS No.
Formula
Concentration
Ethylene glycol
107-21-1
C2H6O2
> 95% (w/w)
Dipotassium phosphate (inhibitor)
7758-11-4
K2HPO4
< 3% (w/w)
Water
7732-18-5
H2O
< 3% (w/w)
Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.
Section 4
First-Aid Measures
Eyes
Rinse with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.
Skin
Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing. Wash with soap. Get medical attention immediately.
Inhalation
Move person to fresh air and keep comfortable for breathing. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention immediately.
Ingestion
Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention immediately.
Most Important Symptoms and Effects
Ingestion may cause nausea, vomiting and abdominal pain; larger amounts may cause systemic poisoning.
Immediate Medical Attention and Special Treatment
Treat symptomatically. Get medical attention if symptoms develop or persist.
Section 5
Fire-Fighting Measures
Suitable Extinguishing Media
Use water spray, alcohol-resistant foam, dry chemical, or CO2. Use measures appropriate to local circumstances.
Unsuitable Extinguishing Media
Do not use a solid water stream as it may scatter and spread fire.
Specific Hazards Arising from the Chemical
Containers may rupture when heated.
Protective Equipment
Wear self-contained breathing apparatus and full protective clothing.
Hazardous Combustion Products
Carbon monoxide and carbon dioxide on combustion; aldehydes and other carbonyl compounds when overheated.
Section 6
Accidental Release Measures
Personal Precautions
Use PPE as described in Section 8. Ensure adequate ventilation. Evacuate personnel to safe areas.
Environmental Precautions
Prevent leakage or spillage from entering drains, sewers, or waterways.
Containment & Cleanup
Absorb with inert material. Collect in appropriate waste container. Dispose per applicable regulations.
Section 7
Handling and Storage
Safe Handling
Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.
Safe Storage
Store in a cool, dry, well-ventilated area. Keep away from incompatible materials (see Section 10). Keep containers tightly closed.
Specific Storage Precautions
Keep tightly closed (hygroscopic) in a cool, dry place away from oxidizers. Store separately from food and drink.
Use adequate ventilation. Provide eyewash stations and quick-drench showers accessible to areas of use.
Eye/Face Protection
Wear chemical safety goggles or face shield.
Skin Protection
Wear chemical-resistant gloves and protective clothing.
Respiratory Protection
Use NIOSH-approved respirator if exposure limits are exceeded or irritation occurs.
Exposure limits sourced from NIOSH Pocket Guide, OSHA 29 CFR 1910.1000 and ACGIH TLVs.
Section 9
Physical & Chemical Properties
Appearance
Clear, colorless viscous liquid
Odor
Odorless
Odor Threshold
No data available
pH
8.5–10.5 (50% aqueous solution)
Melting Point / Freezing Point
-13 °C (9 °F)
Boiling Point
196–198 °C (385–388 °F) at 760 mmHg
Flash Point
111 °C (232 °F), closed cup
Evaporation Rate
No data available
Flammability (solid, gas)
No data available
Upper/Lower Flammability or Explosive Limits
No data available
Vapor Pressure
0.12 mmHg (0.016 kPa) at 20 °C
Vapor Density
No data available
Relative Density
1.12–1.13 at 20 °C (water = 1)
Solubility
Completely miscible with water
Partition Coefficient (n-octanol/water)
log Kow -1.36
Auto-ignition Temperature
413 °C (775 °F)
Decomposition Temperature
No data available
Viscosity
16.1 mPa·s at 25 °C
Particle Characteristics
Not applicable
Form
Liquid
Density
1.115 at 68 °F (USCG, 1999) - Denser than water; will sink
Refractive Index
1.4300 - 1.4370
Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.
Section 10
Stability and Reactivity
Reactivity
Not reactive under normal conditions of use and storage.
Chemical Stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing conditions.
Conditions to Avoid
High heat (above 40 °C in storage), open flame, and moisture (hygroscopic).
Incompatible Materials
Strong oxidizing agents, strong acids and bases, aldehydes, alkali and alkaline-earth metals, aluminum compounds.
Hazardous Decomposition Products
Carbon monoxide and carbon dioxide on combustion; aldehydes and other carbonyl compounds when overheated.
Section 11
Toxicological Information
See below for route-specific acute toxicity data.
Likely Routes of Exposure
Inhalation, skin contact, eye contact, ingestion.
Symptoms
Ingestion may cause nausea, vomiting and abdominal pain; larger amounts may cause systemic poisoning.
Delayed and Chronic Effects
Prolonged or repeated exposure may damage organs.
Acute toxicity
Route
Value
LD50 Oral (rat)
4,700–7,712 mg/kg (rat). Human lethal dose about 1,400–1,600 mg/kg, the basis for H302.
LD50 Dermal (rabbit)
> 10,600 mg/kg
LC50 Inhalation (rat, 4h)
> 2.5 mg/L (aerosol, 6 h)
Carcinogen Classification
Carcinogen classification
Agency
Status
IARC
Not evaluated. See Section 2 for GHS hazard classification.
NTP
Not evaluated. See Section 2 for GHS hazard classification.
OSHA
Not evaluated. See Section 2 for GHS hazard classification.
Section 12
Ecological Information
Ecotoxicity
Daphnia EC50: 10000 mg/L (48 h, Daphnia magna (freshwater, static))
Persistence & Degradability
Not persistent; low bioconcentration, not expected to volatilize
Bioaccumulative Potential
log Kow −1.36
Mobility in Soil
Very high mobility in soil (estimated Koc ≈ 0.2)
Section 13
Disposal Considerations
Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.
EPA RCRA Waste Codes
Not a listed or characteristic hazardous waste as supplied; used glycol may pick up metals and become hazardous — test before disposal.
Section 14
Transport Information
Not regulated for transport under US DOT 49 CFR Subchapter C, IMDG, or IATA DGR in packages holding less than the reportable quantity below.
Hazardous substance (49 CFR 171.8)
A single package holding 5,000 lb (2,270 kg), about 530 US gal, or more of this product contains the reportable quantity (RQ) of a hazardous substance and is regulated as a hazardous material.
Ethylene glycol (CAS 107-21-1) 5,000 lb (2,270 kg), about 540 US gal. EPCRA Section 313 (TRI) listed, de minimis 1.0%.
SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.
Section 16
Other Information
Revision Date
Format
16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.
Disclaimer: The information provided in this Safety Data Sheet is correct to the best of our knowledge at the date of publication. It relates only to the specific product identified and does not relate to its use in combination with other materials. ALLIANCE CHEMICAL MAKES NO WARRANTY, EXPRESS OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. ALLIANCE CHEMICAL DOES NOT ASSUME LIABILITY FOR LOSS, INJURY, DAMAGE, OR EXPENSE ARISING FROM THE HANDLING, STORAGE, USE, OR DISPOSAL OF THIS PRODUCT.
Alliance Chemical, 204 South Edmond Street, Taylor, TX 76574. Published by Alliance Chemical from first-party canonical product data. Our authority is hands-on chemical handling, DOT/GHS-compliant shipping, and government-registered distribution — not bench chemistry. This Safety Data Sheet is prepared from the regulatory data on file for this product.