Methyl Isobutyl Ketone (MIBK) Technical Grade

Product Identifier

Methyl Isobutyl Ketone (MIBK) Technical Grade

Grade

Technical Grade

CAS Number

108-10-1

Chemical Formula

C6H12O

Molecular Weight

100.16 g/mol

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Synonyms

4-Methyl-2-pentanone; isobutyl methyl ketone; hexone; MIBK

Recommended Use

Solvent for coatings, lacquers, inks, adhesives and resins; extraction solvent (metallurgy, dewaxing); chemical intermediate.

Restrictions on Use

For industrial and laboratory use. Suspected of causing cancer: obtain special instructions and avoid exposure. Highly flammable: keep away from ignition sources.

Classification

• Flammable liquids, Category 2
• Serious eye damage/eye irritation, Category 2A
• Acute toxicity (inhalation), Category 4
• Specific target organ toxicity, single exposure, Category 3 (respiratory tract irritation)
• Carcinogenicity, Category 2

Signal Word

Danger

Hazard Statements

• EUH066Repeated exposure may cause skin dryness or cracking
• H225Highly flammable liquid and vapor
• H319Causes serious eye irritation
• H332Harmful if inhaled
• H335May cause respiratory irritation
• H351Suspected of causing cancer

Precautionary Statements

• P201Obtain special instructions before use.
• P202Do not handle until all safety precautions have been read and understood.
• P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P233Keep container tightly closed.
• P240Ground and bond container and receiving equipment.
• P241Use explosion-proof electrical, ventilating, and lighting equipment.
• P242Use non-sparking tools.
• P243Take precautionary measures against static discharge.
• P260Do not breathe dust, fume, gas, mist, vapors or spray.
• P261Avoid breathing dust, fume, gas, mist, vapors or spray.
• P264Wash hands and face thoroughly after handling.
• P271Use only outdoors or in a well-ventilated area.
• P280Wear protective gloves, protective clothing, and eye/face protection.
• P303+P361+P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
• P304+P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313IF exposed or concerned: Get medical advice or attention.
• P312Call a POISON CENTER or doctor if you feel unwell.
• P337+P313If eye irritation persists: Get medical advice or attention.
• P370+P378In case of fire: Use alcohol-resistant foam, CO2 or dry chemical powder to extinguish.
• P403+P233Store in a well-ventilated place. Keep container tightly closed.
• P403+P235Store in a well-ventilated place. Keep cool.
• P405Store locked up.
• P501Dispose of contents and container in accordance with local, regional, national, and international regulations.

Classification, hazard (H) and precautionary (P) statements and pictograms per OSHA HCS 2024 (29 CFR 1910.1200, Appendices A–C), aligned with GHS Rev. 7.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.

Skin

Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing. Wash with soap. Get medical attention immediately.

Inhalation

Move person to fresh air and keep comfortable for breathing. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention immediately.

Ingestion

Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention immediately.

Most Important Symptoms and Effects

• Eye contact causes irritation: redness, pain and tearing.
• Repeated exposure may cause skin dryness or cracking.
• Inhalation may irritate the nose, throat and respiratory tract (coughing, sore throat).
• Inhalation may cause coughing, shortness of breath and headache; high concentrations may cause systemic poisoning.

Immediate Medical Attention and Special Treatment

• Treat symptomatically. Get medical attention if symptoms develop or persist.

Suitable Extinguishing Media

Alcohol-resistant foam, CO2, dry chemical powder. Water spray may be used to cool fire-exposed containers.

Unsuitable Extinguishing Media

Do not use a solid water stream — may scatter and spread fire.

Specific Hazards Arising from the Chemical

Vapors are heavier than air and may form explosive mixtures with air; they can travel to a source of ignition and flash back. Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Carbon monoxide and carbon dioxide on combustion.

Personal Precautions

Use PPE as described in Section 8. Ensure adequate ventilation. Evacuate personnel to safe areas.

Hazard-Specific Precautions

Eliminate all ignition sources. Use non-sparking tools and explosion-proof equipment; ground and bond containers during cleanup.

Environmental Precautions

Prevent leakage or spillage from entering drains, sewers, or waterways.

Containment & Cleanup

Absorb with inert material. Collect in appropriate waste container. Dispose per applicable regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area away from heat, sparks, and open flame. Keep away from incompatible materials (see Section 10). Keep containers tightly closed. Ground and bond containers when transferring material.

Specific Storage Precautions

Keep tightly closed in a cool, well-ventilated flammables area out of sunlight, away from ignition sources and oxidizers. Store locked up. Ground and bond containers.

Occupational Exposure Limits

Engineering Controls

Use adequate ventilation. Provide eyewash stations and quick-drench showers accessible to areas of use.

Eye/Face Protection

Wear chemical safety goggles or face shield.

Skin Protection

Wear chemical-resistant gloves and protective clothing.

Respiratory Protection

Use a NIOSH-approved respirator with organic vapor cartridges. For confined spaces or exposures above the OEL, use supplied-air respiratory protection.

Exposure limits sourced from NIOSH Pocket Guide, OSHA 29 CFR 1910.1000 and ACGIH TLVs.

Appearance

Clear, colorless liquid

Odor

Sweet, camphor-like

Odor Threshold

No data available

pH

No data available

Melting Point / Freezing Point

-84 °C (-119 °F)

Boiling Point

114–117 °C (237–243 °F)

Flash Point

14–17 °C (57–63 °F), closed cup

Evaporation Rate

1.6 (n-butyl acetate = 1)

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

LEL 1.2% / UEL 8.0% (v/v in air)

Vapor Pressure

15–16 mmHg (20–21.5 hPa) at 20 °C

Vapor Density

3.45 (air = 1)

Relative Density

0.799–0.803 at 20 °C (water = 1)

Solubility

Slightly soluble in water (17–20 g/L at 20 °C); miscible with alcohols, ethers and most organic solvents

Partition Coefficient (n-octanol/water)

log Kow 1.3

Auto-ignition Temperature

448–460 °C (838–860 °F)

Decomposition Temperature

No data available

Viscosity

0.6 mPa·s at 20 °C

Particle Characteristics

Not applicable

Form

Liquid

Density

0.802 at 68 °F (USCG, 1999) - Less dense than water; will float

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Heat, sparks, open flame, static discharge and direct sunlight. On long storage in contact with air it may form explosive peroxides — do not distill or evaporate to dryness without testing.

Incompatible Materials

Strong oxidizing agents; strong reducing agents; strong bases.

Hazardous Decomposition Products

Carbon monoxide and carbon dioxide on combustion.

See below for route-specific acute toxicity data.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• Eye contact causes irritation: redness, pain and tearing.
• Repeated exposure may cause skin dryness or cracking.
• Inhalation may irritate the nose, throat and respiratory tract (coughing, sore throat).
• Inhalation may cause coughing, shortness of breath and headache; high concentrations may cause systemic poisoning.

Delayed and Chronic Effects

• Carcinogenicity: may cause or is suspected of causing cancer after long-term exposure (see the carcinogen classification below).
• Repeated skin contact may cause dermatitis (dry, cracked skin).

Carcinogen Classification

Ecotoxicity

Algae ErC50: 400 mg/L (96 h, Selenastrum capricornutum); Fish LC50: 505 mg/L (96 h, Pimephales promelas)

Persistence & Degradability

Not persistent; volatilizes (air half-life ~30 d) — Readily biodegradable (84% ThBOD, MITI)

Bioaccumulative Potential

log Kow 1.31, BCF 3 (estimated; low)

Mobility in Soil

High soil mobility (estimated Koc 70)

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

EPA RCRA Waste Codes

U161 when discarded unused; F003 as a spent solvent; D001 (ignitable).

If discarded, this material may be an ignitable hazardous waste (EPA RCRA D001, 40 CFR 261.21(a)(1): flash point below 60 °C; aqueous solutions with less than 24% alcohol by volume are excluded). The waste generator must make the final hazardous-waste determination.

US DOT (49 CFR)

UN Number

UN1245

Proper Shipping Name

Methyl isobutyl ketone

Hazard Class

3

Packing Group

II

Additional US DOT Requirements

Inner packagings of 1 L or less may ship as Limited Quantity (49 CFR 173.150(b)). Not a marine pollutant.

IMDG / IATA classifications may differ from US DOT. Verify current regulations before international shipment.

CERCLA Reportable Quantity (RQ)

Methyl isobutyl ketone (CAS 108-10-1) 5,000 lb (2,270 kg), about 750 US gal; no single Alliance package reaches it (largest: 55-gal drum). Clean Air Act hazardous air pollutant.

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.

Revision Date

2026-10-08

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.