Petroleum Ether ACS Reagent Grade

Product Identifier

Petroleum Ether ACS Reagent Grade

Grade

ACS Reagent

CAS Number

8032-32-4

Chemical Formula

C5-C6 Hydrocarbons

Molecular Weight

70.0 g/mol

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Synonyms

Ligroine; petroleum spirit; benzine (35–60 °C boiling fraction)

Recommended Use

Laboratory solvent (ACS reagent): extraction of fats and oils, chromatography and recrystallization.

Restrictions on Use

Not for use as a fuel or in consumer products. Extremely flammable and may cause cancer: use only with adequate ventilation, away from ignition sources, by trained personnel.

Classification

• Flammable liquids, Category 2
• Aspiration hazard, Category 1
• Specific target organ toxicity, single exposure, Category 3 (narcotic effects)
• Germ cell mutagenicity, Category 1
• Carcinogenicity, Category 1

Signal Word

Danger

Hazard Statements

• H225Highly flammable liquid and vapor
• H304May be fatal if swallowed and enters airways
• H336May cause drowsiness or dizziness
• H340May cause genetic defects
• H350May cause cancer

Precautionary Statements

• P201Obtain special instructions before use.
• P202Do not handle until all safety precautions have been read and understood.
• P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P233Keep container tightly closed.
• P240Ground and bond container and receiving equipment.
• P241Use explosion-proof electrical, ventilating, and lighting equipment.
• P242Use non-sparking tools.
• P243Take precautionary measures against static discharge.
• P261Avoid breathing dust, fume, gas, mist, vapors or spray.
• P271Use only outdoors or in a well-ventilated area.
• P280Wear protective gloves, protective clothing, and eye/face protection.
• P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor.
• P303+P361+P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
• P304+P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313IF exposed or concerned: Get medical advice or attention.
• P312Call a POISON CENTER or doctor if you feel unwell.
• P331Do NOT induce vomiting.
• P370+P378In case of fire: Use alcohol-resistant foam, CO2 or dry chemical powder to extinguish.
• P403+P233Store in a well-ventilated place. Keep container tightly closed.
• P403+P235Store in a well-ventilated place. Keep cool.
• P405Store locked up.
• P501Dispose of contents and container in accordance with local, regional, national, and international regulations.

Classification, hazard (H) and precautionary (P) statements and pictograms per OSHA HCS 2024 (29 CFR 1910.1200, Appendices A–C), aligned with GHS Rev. 7.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.

Skin

Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing. Wash with soap. Get medical attention immediately.

Inhalation

Move person to fresh air and keep comfortable for breathing. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention immediately.

Ingestion

Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention immediately.

Most Important Symptoms and Effects

• Aspiration into the lungs, for example during vomiting, may cause chemical pneumonitis, which can be fatal.
• Inhalation of vapors may cause drowsiness, dizziness, headache and nausea.

Immediate Medical Attention and Special Treatment

• Aspiration hazard: if swallowed, do not induce vomiting and get medical attention immediately. Note to physician: observe for chemical pneumonitis; protect the airway before any gastric procedure.

Suitable Extinguishing Media

Alcohol-resistant foam, CO2, dry chemical powder. Water spray may be used to cool fire-exposed containers.

Unsuitable Extinguishing Media

Do not use a solid water stream — may scatter and spread fire.

Specific Hazards Arising from the Chemical

Vapors are heavier than air and may form explosive mixtures with air; they can travel to a source of ignition and flash back. Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Carbon monoxide, carbon dioxide and unburned hydrocarbons on combustion.

Personal Precautions

Use PPE as described in Section 8. Ensure adequate ventilation. Evacuate personnel to safe areas.

Hazard-Specific Precautions

Eliminate all ignition sources. Use non-sparking tools and explosion-proof equipment; ground and bond containers during cleanup.

Environmental Precautions

Prevent leakage or spillage from entering drains, sewers, or waterways.

Containment & Cleanup

Absorb with inert material. Collect in appropriate waste container. Dispose per applicable regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area away from heat, sparks, and open flame. Keep away from incompatible materials (see Section 10). Keep containers tightly closed. Ground and bond containers when transferring material.

Specific Storage Precautions

Keep tightly closed in a cool, well-ventilated flammables area away from heat, ignition sources and oxidizers. Ground and bond containers. Store locked up.

Occupational Exposure Limits

Engineering Controls

Use adequate ventilation. Provide eyewash stations and quick-drench showers accessible to areas of use.

Eye/Face Protection

Wear chemical safety goggles or face shield.

Skin Protection

Wear chemical-resistant gloves and protective clothing.

Respiratory Protection

Use a NIOSH-approved air-purifying respirator with cartridges appropriate for the contaminant. For higher exposures or confined spaces, use supplied-air or a powered air-purifying respirator (PAPR).

Exposure limits sourced from NIOSH Pocket Guide, OSHA 29 CFR 1910.1000 and ACGIH TLVs.

Appearance

Clear, colorless liquid

Odor

Petroleum (gasoline-like) odor

Odor Threshold

No data available

pH

No data available

Melting Point / Freezing Point

No data available

Boiling Point

35–60 °C (95–140 °F) boiling range

Flash Point

Below -18 °C (0 °F), closed cup

Evaporation Rate

No data available

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

LEL 1.1% / UEL 5.9% (v/v in air)

Vapor Pressure

About 540 mmHg (724 hPa) at 20 °C

Vapor Density

No data available

Relative Density

0.64–0.66 at 20 °C (water = 1)

Solubility

Insoluble in water; miscible with most organic solvents

Partition Coefficient (n-octanol/water)

No data available

Auto-ignition Temperature

No data available

Decomposition Temperature

No data available

Viscosity

No data available

Particle Characteristics

Not applicable

Form

Liquid

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Heat, sparks, open flame, static discharge and other ignition sources. Vapors are heavier than air and can travel to a distant ignition source and flash back.

Incompatible Materials

Strong oxidizing agents (peroxides, nitric acid, perchlorates, chlorine); strong acids.

Hazardous Decomposition Products

Carbon monoxide, carbon dioxide and unburned hydrocarbons on combustion.

See below for route-specific acute toxicity data.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• Aspiration into the lungs, for example during vomiting, may cause chemical pneumonitis, which can be fatal.
• Inhalation of vapors may cause drowsiness, dizziness, headache and nausea.

Delayed and Chronic Effects

• Carcinogenicity: may cause or is suspected of causing cancer after long-term exposure (see the carcinogen classification below).
• Germ cell mutagenicity: may cause or is suspected of causing genetic defects.

Carcinogen Classification

Ecotoxicity

Data not available. Avoid release to the environment.

Persistence & Degradability

Not Available

Bioaccumulative Potential

Not Available

Mobility in Soil

Not Available

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

EPA RCRA Waste Codes

D001 (ignitable). Not a P- or U-listed waste.

If discarded, this material may be an ignitable hazardous waste (EPA RCRA D001, 40 CFR 261.21(a)(1): flash point below 60 °C; aqueous solutions with less than 24% alcohol by volume are excluded). The waste generator must make the final hazardous-waste determination.

US DOT (49 CFR)

UN Number

UN1268

Proper Shipping Name

Petroleum distillates, n.o.s. (Petroleum ether)

Hazard Class

3

Packing Group

II

Additional US DOT Requirements

Inner packagings of 1 L or less may ship as Limited Quantity (49 CFR 173.150(b)).

IMDG / IATA classifications may differ from US DOT. Verify current regulations before international shipment.

CERCLA Reportable Quantity (RQ)

Not a CERCLA hazardous substance (petroleum exclusion, CERCLA §101(14)); no RQ. Not an EPCRA Section 313 chemical as such.

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.

Revision Date

2026-10-07

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.