Trisodium Phosphate Dodecahydrate - ACS Reagent Grade

Product Identifier

Trisodium Phosphate Dodecahydrate - ACS Reagent Grade

Grade

ACS Reagent

CAS Number

10101-89-0

Molecular Weight

380.12 g/mol

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Recommended Use

Industrial / laboratory chemical. See Section 7.

Restrictions on Use

No restrictions identified beyond the conditions of safe use in Sections 7 and 8.

Classification

• Skin corrosion/irritation, Category 2
• Serious eye damage/eye irritation, Category 2A
• Specific target organ toxicity, single exposure, Category 3 (respiratory tract irritation)

Signal Word

Warning

Hazard Statements

• H315Causes skin irritation
• H319Causes serious eye irritation
• H335May cause respiratory irritation

Precautionary Statements

• P260Do not breathe dust, fume, gas, mist, vapors or spray.
• P261Avoid breathing dust, fume, gas, mist, vapors or spray.
• P264Wash hands and face thoroughly after handling.
• P271Use only outdoors or in a well-ventilated area.
• P280Wear protective gloves, protective clothing, and eye/face protection.
• P302+P352IF ON SKIN: Wash with plenty of water and soap.
• P304+P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312Call a POISON CENTER or doctor if you feel unwell.
• P321Specific treatment (see first-aid information on this label).
• P332+P313If skin irritation occurs: Get medical advice or attention.
• P337+P313If eye irritation persists: Get medical advice or attention.
• P362Take off contaminated clothing and wash before reuse.
• P363Wash contaminated clothing before reuse.
• P403+P233Store in a well-ventilated place. Keep container tightly closed.
• P405Store locked up.
• P501Dispose of contents and container in accordance with local, regional, national, and international regulations.

Classification, hazard (H) and precautionary (P) statements and pictograms per OSHA HCS 2024 (29 CFR 1910.1200, Appendices A–C), aligned with GHS Rev. 7.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.

Skin

Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing. Wash with soap. Get medical attention immediately.

Inhalation

Move person to fresh air and keep comfortable for breathing. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention immediately.

Ingestion

Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention immediately.

Most Important Symptoms and Effects

• Eye contact causes irritation: redness, pain and tearing.
• Skin contact causes irritation: redness, itching and pain; repeated contact may dry and crack the skin.
• Inhalation may irritate the nose, throat and respiratory tract (coughing, sore throat).

Immediate Medical Attention and Special Treatment

• Treat symptomatically. Get medical attention if symptoms develop or persist.

Suitable Extinguishing Media

Use water spray, alcohol-resistant foam, dry chemical, or CO2. Use measures appropriate to local circumstances.

Unsuitable Extinguishing Media

Do not use a solid water stream as it may scatter and spread fire.

Specific Hazards Arising from the Chemical

Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Phosphorus oxides and sodium oxides.

Personal Precautions

Use PPE as described in Section 8. Ensure adequate ventilation. Evacuate personnel to safe areas.

Environmental Precautions

Prevent leakage or spillage from entering drains, sewers, or waterways.

Containment & Cleanup

Absorb with inert material. Collect in appropriate waste container. Dispose per applicable regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area. Keep away from incompatible materials (see Section 10). Keep containers tightly closed.

Specific Storage Precautions

Keep containers tightly closed in a dry, cool, well-ventilated place away from incompatible materials, food and animal feed. Hygroscopic; keep sealed to avoid moisture pickup and caking.

Occupational Exposure Limits

No established occupational exposure limits.

Engineering Controls

Use adequate ventilation. Provide eyewash stations and quick-drench showers accessible to areas of use.

Eye/Face Protection

Wear chemical safety goggles or face shield.

Skin Protection

Wear chemical-resistant gloves and protective clothing.

Respiratory Protection

Use a NIOSH-approved respirator (N95/P100 for particulate, organic vapor or acid gas cartridge as appropriate to the substance) when exposure limits may be exceeded or visible mist or dust is generated.

Appearance

White crystalline powder, hygroscopic

Odor

No data available

Odor Threshold

No data available

pH

11.5 - 12.5

Melting Point / Freezing Point

Melting point equals 164 to 170 ° F

Boiling Point

100 °C

Flash Point

N/A

Evaporation Rate

No data available

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

No data available

Vapor Pressure

No data available

Vapor Density

No data available

Relative Density

No data available

Solubility

Soluble in water

Partition Coefficient (n-octanol/water)

No data available

Auto-ignition Temperature

No data available

Decomposition Temperature

No data available

Viscosity

No data available

Particle Characteristics

No data available

Form

Solid

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Dust formation; moisture (hygroscopic, causes caking); heat (loses water of crystallization from about 75 °C / 167 °F); mixing with acids.

Incompatible Materials

Strong acids (strong exothermic reaction); strong oxidizing agents; magnesium; metals in solution (flammable hydrogen gas).

Hazardous Decomposition Products

Phosphorus oxides and sodium oxides.

See Section 2 for GHS hazard classification.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• Eye contact causes irritation: redness, pain and tearing.
• Skin contact causes irritation: redness, itching and pain; repeated contact may dry and crack the skin.
• Inhalation may irritate the nose, throat and respiratory tract (coughing, sore throat).

Delayed and Chronic Effects

• Repeated skin contact may cause dermatitis (dry, cracked skin).

Numerical Measures of Toxicity

No data available

Carcinogen Classification

Ecotoxicity

Fish LC50: 28.5 mg/L (96 h, Gambusia affinis — pH-driven; data for ANHYDROUS TSP (7601-54-9), bridged (24-h 88.3 mg/L; pH 7.4–10.3))

Persistence & Degradability

Toxicity pH-driven (strongly alkaline in water); endpoints reported under anhydrous TSP (CAS 7601-54-9)

Bioaccumulative Potential

Not Available

Mobility in Soil

Not Available

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

Not regulated for transport under US DOT 49 CFR Subchapter C, IMDG, or IATA DGR in packages holding less than the reportable quantity below.

Hazardous substance (49 CFR 171.8)

A single package holding 5,000 lb (2,270 kg) or more of this product contains the reportable quantity (RQ) of a hazardous substance and is regulated as a hazardous material.

Reportable quantity (49 CFR 172.101 Appendix A)

Sodium phosphate, tribasic — RQ 5,000 lb (2,270 kg)

Shipping description (package at or above the RQ)

UN3077, Environmentally hazardous substance, solid, n.o.s. (Sodium phosphate, tribasic), 9, III, RQ

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.

Revision Date

2026-10-13

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.