Industrial chemicals · Taylor, TXTechnical Data Sheet
Technical Data Sheet
Isopropyl Alcohol 50% USP Grade
USP · 50%
- CAS number
- 67-63-0
- UN number
- UN1219
- Hazard class · packing group
- 3 · PG II
- Structure
Structure · PubChem - Grade
- USP · 50%
- Signal word
- Danger
- Hazards
- Proper shipping name
- Isopropanol or isopropyl alcohol
Last reviewed 2026-06-18 by Andre Taki, Chief Commercial Officer.
Identity & Composition
- Product Name
- Isopropyl Alcohol 50% USP Grade
- Alliance Code
- isopropyl-alcohol-50-usp-grade
- Grade
- USP
- Concentration
- 50%
- CAS Number
- 67-63-0PubChem
- Formula
- C3H8OPubChem
- Molecular Weight
- 60.10PubChem
- Product Type
- Solution
Specifications
| Test | Specification | Typical | Method | Source |
|---|---|---|---|---|
| Assay (isopropyl alcohol) | 48-52 % | 50.1 % | Specific gravity | Interpreted |
| 1-Propanol | ≤ 0.0505 % | 0.00063 % | — | Interpreted |
| 2-Butanol | ≤ 0.0505 % | 0.00021 % | — | Interpreted |
| Acidity | NMT 0.35 mL of 0.020 N sodium hydroxide | 0.07 | Titration with 0.020 N sodium hydroxide, 50 mL sample | Interpreted |
| Benzene | ≤ 1.01 ppm | 0.043 ppm | — | Interpreted |
| Diisopropyl ether | ≤ 0.0505 % | 0.0029 % | — | Interpreted |
| Ethyl ether | ≤ 0.0505 % | 0.00052 % | — | Interpreted |
| Total volatile impurities | ≤ 0.505 % | 0.0058 % | — | Interpreted |
| Each other individual known impurity (ethyl ether, acetone, diisopropyl ether, 1-propanol, 2-butanol) | 0.048 % max | 0.00013 % | Gas chromatography | Interpreted |
| Methanol | 0.0097 % max | 0.000058 % | Gas chromatography | Interpreted |
| Total organic impurities | 0.48 % max | 0.0047 % | Gas chromatography | Interpreted |
| Titrable Base | 0.000043 meq/g max | 0.000009 meq/g | — | Interpreted |
| Carbonyl compounds (as acetone) | 0.00087 % max | 0.00018 % | — | Interpreted |
| Limit of nonvolatile residue | does not exceed 2.5 mg (0.005%) | Passes test | Evaporate 50 mL on a steam bath to dryness, heat at 105° for 1 hour | Interpreted |
| Composition | 50 % isopropyl alcohol / 50 % deionized water, by volume | Conforms | By formulation; confirmed by specific gravity | Interpreted |
Values are reproduced from the current product reference. Source labels do not by themselves establish a supplier guarantee or a test result for your lot. Confirm applicable acceptance limits and request lot-specific documentation.
Available GradesSame CAS, alternate grades and concentrations
| Grade | Concentration | Typical Assay | SKU | TDS |
|---|---|---|---|---|
| This grade USP | 50% | — | current | current |
| ACS Reagent | 99.9% | — | isopropyl-alcohol-99-9-acs-reagent-grade | View TDS → |
| Technical | 99% | — | isopropyl-alcohol-99 | View TDS → |
| USP Grade | 70% | — | isopropyl-alcohol-70-usp-grade | View TDS → |
| Technical | 60% | — | isopropyl-alcohol-60-technical-grade | View TDS → |
| USP | 60% | — | isopropyl-alcohol-60-usp-grade | View TDS → |
| Technical | 50% | — | isopropyl-alcohol-50-technical-grade | View TDS → |
Typical assay shown is the rolling-window mean from the sibling product's most recent lots. Grade selection drives downstream end-use — verify the sibling grade matches your specification before substitution.
Physical & Chemical Properties
| Property | Value | Source |
|---|---|---|
| Appearance | Clear, colorless liquid with mild alcohol odor | Adjudicated |
| Color | NMT 5 | Interpreted |
| Odor | Alcohol-like odor | Adjudicated |
| Specific Gravity | About 0.93 at 20 °C (water = 1) | Adjudicated |
| Boiling Point | About 82 °C (180 °F) | Adjudicated |
| Melting Point | -21 to -23 °C (-6 to -9 °F), freezing point of a 50% v/v isopropyl alcohol–water solution (published tables) | Adjudicated |
| Flash Point | 12–22 °C (54–72 °F), closed cup | Adjudicated |
| Vapor Density | 2.1 (air = 1) | Adjudicated |
| Solubility (water) | Completely miscible with water | Adjudicated |
Polar solvent — purity vs. intended end-use (electronics, pharma, general industrial) is the dominant grade consideration. See application guidance for grade selection.
Materials of ConstructionService envelope ≈ 50%
| Material | Rating | Max T (°C) | Notes | Source |
|---|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. | Parker O-ring Chemical Compatibility |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters | Cole-Parmer Chemical Compatibility |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. | Parker O-ring Chemical Compatibility |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing | Cole-Parmer Chemical Compatibility |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. | Cole-Parmer Chemical Compatibility |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. | Cole-Parmer Chemical Compatibility |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. | Cole-Parmer Chemical Compatibility |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact | Cole-Parmer Chemical Compatibility |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. | Cole-Parmer Chemical Compatibility |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. | Cole-Parmer Chemical Compatibility |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters | Cole-Parmer Chemical Compatibility |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters | Cole-Parmer Chemical Compatibility |
Ratings reflect the service envelope (concentration × temperature) shown. Always confirm against your specific duty cycle and contact-time before equipment selection. The most cautious rating across overlapping references is shown.
Materials Selection Tool
Showing 12 of 12 material ratings within the selected envelope.
| Material | Rating | Max T (°C) | Notes |
|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters |
Regulatory & Transport
DOT / 49 CFR
- UN Number
- UN1219Adjudicated
- Hazard Class
- 3Adjudicated
- Packing Group
- IIAdjudicated
- Proper Shipping Name
- Isopropanol or isopropyl alcoholAdjudicated
GHS / OSHA HCS 2024
- Signal Word
- DangerAdjudicated
- H-Codes (Hazard Statements)
- H225, H319, H336ECHA C&L Inventory
- P-Codes (Precautionary Statements)
- P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, P501ECHA C&L Inventory
Occupational Exposure Limits
- OSHA PEL (29 CFR 1910.1000)
- 400 ppm TWAOSHA 29 CFR 1910.1000
- ACGIH TLV
- 200 ppm TWA / 400 ppm STELAdjudicated
- NIOSH REL
- 400 ppm TWA / 500 ppm STELNIOSH Pocket Guide
- NIOSH IDLH
- 2000 ppmNIOSH Pocket Guide
Transport descriptions reflect 49 CFR 172.101 lookup at time of publication. Sourced data: NIOSH Pocket Guide for REL/IDLH, OSHA Z-Tables for PEL. Always verify against the latest regulatory text before shipment-critical decisions.
Health & Fire Hazard
Acute Toxicology
- LD₅₀ Oral (rat)
- 4,700–5,840 mg/kg (isopropyl alcohol)Adjudicated
- LD₅₀ Dermal (rabbit)
- 12,800–16,400 mg/kg (isopropyl alcohol)Adjudicated
- LC₅₀ Inhalation (rat, 4 h)
- 72.6 mg/L (isopropyl alcohol vapor)Adjudicated
Acute toxicology values from SDS Section 11 or NIOSH RTECS.
Supplier Qualification Packet
One zipped download containing the TDS, SDS, latest lot COA (when available), and a fresh Letter of Continuing Guaranty for Isopropyl Alcohol 50% USP Grade. Every file included is SHA-256 hashed and listed in a manifest your QA team can audit.
Catalog EquivalentsCross-reference vs major chemical suppliers
Sigma-Aldrich
| SKU | Grade | Conc. | Match | Notes |
|---|---|---|---|---|
| 190764 | ACS Reagent | 99.5% | Unverified candidate | ACS Reagent ≥99.5% |
ThermoFisher
| SKU | Grade | Conc. | Match | Notes |
|---|---|---|---|---|
| A416-4 | ACS | 99.5% | Unverified candidate | Optima LC/MS grade equivalent |
Cross-references are informational. Confirm against the manufacturer's current specification before substitution. Competitor trademarks are property of their respective owners.
Applications
Cleaning and degreasing solution; surface and equipment wipe-down; general solvent blend.Adjudicated
Restrictions on Use: For external and surface use only. Do not drink. Highly flammable: keep away from heat and open flame.
Storage & Handling
- Recommended Storage
- Keep tightly closed in a cool, well-ventilated flammables area away from ignition sources and oxidizers. Ground and bond containers.Adjudicated
- Handling Precautions
- Use chemical-resistant gloves and splash goggles. Bond and ground during transfer to prevent static accumulation. Eliminate ignition sources within vapor envelope.Class-level guidance — not product-specific; the SDS controls.
- Incompatibilities
- Strong oxidizing agents (peroxides, nitric acid, perchlorates, hypochlorites), strong acids, acid anhydrides, halogens, and alkali metals (release hydrogen).Adjudicated
- Shelf Life
- Consult Technical Services for product-specific shelf life
For full hazard, PPE, and emergency response guidance, refer to the Safety Data Sheet (SDS) for this product. The SDS controls in all cases where guidance differs.
Packaging & Logistics
Shipping Description (US DOT)
UN1219, Isopropanol or isopropyl alcohol, 3, PG II
Sourced from 49 CFR 172.101. Confirm against shipping documents and carrier requirements before tender.
NMFC Class
70
Placard
Flammable Liquid
Packing Group
PG II
Revision History
Last reviewed 2026-06-18 by Andre Taki, Chief Commercial Officer, DOT Hazmat–certified (49 CFR 172.704).
| Version | Date | Change | Trigger |
|---|---|---|---|
| 1.9 | 2026-10-14 | Canonical data updated: 2 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.8 | 2026-10-08 | Canonical data updated: 19 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.7 | 2026-10-05 | Canonical data updated: 3 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.6 | 2026-10-03 | Canonical data updated: 1 field changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.5 | 2026-09-30 | Canonical data updated: 3 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.4 | 2026-09-10 | Canonical data updated: 1 field changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.3 | 2026-08-05 | Canonical data updated: 3 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.2 | 2026-07-22 | Canonical data updated: 2 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.1 | 2026-06-18 | Canonical data re-verified: 3 fields updated against independent vendor SDSs, CLP Annex VI, 49 CFR, and OSHA HazCom 2024 (GHS classification, hazard/precautionary codes, signal word, physical properties as applicable).
| canonical_change |
| 1.0 | 2026-05-20 | Initial URL-first TDS published from canonical chemistry registry. | initial |
This Technical Data Sheet is provided for technical reference. The Safety Data Sheet (SDS) controls in all cases where guidance differs. Values reflect Alliance Chemical canonical data at time of generation; subsequent revisions are recorded in the Revision History above.