Handbook / Version 1.0 / September 2026

From cooling requirements to a purchasing brief.

A reference for connecting system boundaries, fluid specifications, and the evidence needed for procurement.

Source-based editorial edition. Independent specialist review pending. No original testing or product qualification is claimed.

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Chapter 1

Start with the loop, then specify the fluid

Trace the heat and identify the fluid boundary

A cooling diagram is the starting point for a useful fluid specification. Identify the equipment loop, its heat exchanger, and the facility system that ultimately rejects heat. A heat exchanger can transfer heat between separate fluids; it does not imply that both sides share one fluid specification.

The interactive map in this collection shows one common liquid-to-liquid arrangement. Record the actual arrangement for your project, including any equipment-specific or immersion circuits.

Build a requirements record for each circuit

Our proposed worksheet keeps the equipment requirement, the proposed material, and the supporting evidence in separate fields. This makes unresolved questions visible before a purchase order is issued.

  • Which equipment model and manual revision apply?
  • Who owns approval of the fluid and any substitution?
  • Which materials contact the fluid, including hoses, seals, and connectors?
  • What operating and storage conditions does the equipment supplier specify?
  • Is this an initial fill, replenishment, or a proposed fluid change?

Keep immersion applications distinct

ASHRAE describes immersion arrangements using dielectric fluids. An aqueous cooling-fluid selection should not be carried over to an immersion bath. Begin with the immersion equipment requirements and the evidence for the specific fluid.

Chapter 2

Glycol percentage is the beginning of the specification

Identify the complete formulation

Dow describes DOWFROST LC 25 as a formulated coolant with a specialized inhibitor package. Its product information is evidence about that named formulation. It does not establish equivalence with another fluid sharing the same nominal glycol concentration.

Use the actual equipment requirement

The NVIDIA CS8500 manual calls for a ready-to-use PG-25 coolant in that system. Treat this as a requirement for the identified equipment, not a universal instruction for every data center. Record the approved fluid designation and confirm the applicable manual revision with the equipment owner.

Make concentration unambiguous

On a purchasing worksheet, record the concentration basis, the supplied condition, and the document that defines the requirement. A percentage without its basis leaves room for an avoidable misunderstanding. Ask the supplier to identify the formulation and documentation for the exact product being quoted.

  • Is concentration specified by mass or volume?
  • Is the material ready to use or a concentrate?
  • What evidence supports the proposed formulation under the intended conditions?
  • Does the existing system contain the same fluid?
  • Who must approve a change before procurement proceeds?

Chapter 3

Read the specification, TDS, and COA together

Ask what kind of number you are reading

A typical property describes representative behavior. A purchase specification defines an agreed requirement. A measured lot result describes a particular sample under a stated method. Keep these categories explicit in your comparison; a typical value should not silently become an acceptance limit.

A reference or typical COA is not the measured result for the shipment you receive. Request the applicable lot documentation and check its relationship to the product, lot identifier, and purchase requirement.

Preserve method and conditions

NIST describes metrological traceability in terms of a documented chain of calibrations, with measurement uncertainty considered along that chain. A traceability statement needs supporting context. It is not a substitute for evaluating whether a measurement answers your application question.

Build a comparison that exposes missing evidence

Use one row per requirement. Record the limit and units, source revision, supplier evidence, applicable lot result, and the person responsible for resolving gaps. Mark an unavailable result as unresolved instead of interpreting its absence as a pass.

  • Does the document identify the exact material and concentration?
  • Are temperature, units, and test method stated where relevant?
  • Is this a typical value, limit, or measured result?
  • Does the lot identifier match the received material?
  • Which requirements still require equipment-owner or supplier confirmation?

Chapter 4

Ask better materials-compatibility questions

Start with the complete wetted-material inventory

ASHRAE identifies wetted-material compatibility and serviceability as considerations in coolant selection. The inventory should include the components that can be easy to overlook: seals, hoses, connectors, and the heat exchanger as well as the cold plate.

Ask what the evidence covers

Our qualification checklist asks for the exact fluid, material designation, test conditions, duration, and acceptance criteria behind a compatibility statement. Evidence about one material and condition should not be presented as proof for an entire assembled system.

Open Compute Project maintains cold-plate and coolant working-group resources. Check the status and revision of each document; a working draft and a final specification serve different purposes.

  • Does the evidence cover the proposed formulation?
  • Does it cover the actual material grade or component?
  • What temperatures and exposure conditions were evaluated?
  • What was measured and what counted as acceptable?
  • What remains subject to equipment qualification?

Chapter 5

Plan the purchase through receiving and replenishment

Make the quote request usable

Record the approved product or specification, supplied concentration, required quantity, preferred packaging, delivery timing, and receiving constraints. Distinguish the estimated system fill from the quantity procurement has authorized. Ask the supplier to confirm the available configuration rather than assuming every container size is stocked.

Keep the evidence with the shipment

Our suggested receiving record includes the ordered product identity, delivered label, lot identifier, available lot documentation, container condition, and the person responsible for resolving discrepancies. Preserve the purchasing requirement alongside the received documents so later reviews have context.

  • Which documents must be available before receipt?
  • What storage conditions are specified by the supplier?
  • Can the receiving location handle the proposed containers?
  • Who records the lot and disposition of the material?

Document what is already in the system

For replenishment or a proposed change, identify the existing fluid and the governing equipment instructions before requesting a replacement. Dow recommends assessing compatibility against specific system conditions and equipment requirements; matching a chemical name alone is not sufficient justification for a substitution.

Chapter 6

From cooling research to an engineering question

Optimization research: ask what the model represents

A 2026 preprint by Shrenik Jadhav and Zheng Liu describes a digital twin of Frontier cooling infrastructure, validated against operational data, and evaluates flow and supply-temperature optimization. This brief draws on the abstract of the August 2026 revision; it is not a full methodological review.

The useful follow-up is to examine which measured inputs and operating constraints your own model requires. The reported modeling outcomes do not establish energy savings from an Alliance product or guarantee results at another facility.

Water reuse: identify the intended use

EPA maintains resources on industrial water reuse, including a December 2025 data-center webinar. DOE illustrates how a closed equipment-water circuit can transfer heat into a cooling-tower system. Describing one circuit as closed does not by itself establish the water consumption of the entire facility.

Turn a paper into a decision record

Before changing a specification, document what was demonstrated, the system and conditions studied, the evidence limitations, and what would need local validation. Keep research findings separate from manufacturer requirements and supplier product data.

  • Was the outcome modeled, measured in a test rig, or observed in operation?
  • What conditions limit its applicability?
  • Which input data would your team need?
  • Does it change a purchasing requirement, or only suggest further investigation?

Prepare your requirements

Complete the purchasing worksheet at docs.alliancechemical.com/technical/data-center-cooling#worksheet. Export it for your engineering team or supplier.

Open the worksheet →

Revision 1.0 · September 10, 2026 — Initial editorial edition. Source status and limitations are stated in each chapter.