Industrial chemicals · Taylor, TX
Technical Data Sheet

Technical Data Sheet

Propylene Glycol USP Grade

USP Grade

CAS番号
57-55-6
Alliance Code
propylene-glycol-usp-grade
作成日
2026-09-11
Revision
1.1
Reviewed
2026-06-17 · Andre Taki
2D chemical structure of Propylene Glycol USP Grade
Structure · PubChem
Last reviewed 2026-06-17 by Andre Taki, DOT Hazmat Specialist.

Identity & Composition

製品名
Propylene Glycol USP Grade
Alliance Code
propylene-glycol-usp-grade
Grade
USP Grade
濃度
CAS番号
57-55-6PubChem
化学式
C3H8O2PubChem
分子量
76.09PubChem
製品種別
pure_substance

Specifications

TestSpecificationTypicalMethodSource
Assay (C3H8O2)not less than 99.5 percent99.9 %GC, thermal conductivity detector, 1-m x 4-mm column packed with 5% G16 on support S5, area normalization excluding air and waterInterpreted
Aciditynot more than 0.20 mL of 0.10 N sodium hydroxide is required0.04Titration of 10 mL with 0.10 N sodium hydroxide to phenolphthalein endpointInterpreted
Chloride0.007%0.00003 %USP <221>Interpreted
Heavy metals5 ppm0.5 ppmUSP <231>Interpreted
Identification A (Infrared Absorption)Infrared Absorption 〈197F〉 on undried specimenPasses testUSP <197F>Interpreted
Iron0.50 weight ppm (maximum)0.05 ppmHOC 0290Interpreted
Limit of Diethylene GlycolNMT 0.10%0.003%GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standardInterpreted
Limit of Ethylene GlycolNMT 0.10%0.002%GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standardInterpreted
Residual solventsPassPasses testUSP <467>Interpreted
Residue on ignition0.0070 wt% max (3.5 mg from 50 g)0.0005 wt%Ignition of 50 g, residue moistened with 0.5 mL sulfuric acid and ignited to constant weightInterpreted
Sulfate0.006%0.0005 %USP <221>Interpreted
Suspended matterPassPasses testHOC 0171Interpreted
Waternot more than 0.2%0.03 %USP <921> Method I (Karl Fischer)Interpreted
Elemental impuritiesMeets USP <232> / ICH Q3D oral limitsPasses testUSP <232> / <233>, ICP-MSInterpreted
Microbial enumerationTAMC ≤ 100 CFU/g; TYMC ≤ 10 CFU/gPasses testUSP <61>Interpreted
arsenic1 ppm max0.02 ppmInterpreted
dp189 Deg.C max188.2 °CInterpreted
dpg0.1 %m/m max0.03 %m/mInterpreted
ibp185 Deg.C min186.8 °CInterpreted
pb1 mg/kg max0.01 ppmInterpreted
meg0.001 %m/m max0.0005 %m/mInterpreted
oxidizing substances0.2 ml max0.03Interpreted
po0.001 %m/m max0.0002 %m/mInterpreted
tpg0.03 %m/m max0.006 %m/mInterpreted
residue0.005 % max< 0.001 %Interpreted

Specification values are guaranteed limits. Typical values are representative of production lots and are not guaranteed. Lot-specific certificates of analysis ship with every order.

Available GradesSame CAS, alternate grades and concentrations

Grade濃度Typical AssaySKUTDS
This grade USP Gradecurrentcurrent
60%propylene-glycol-60-inhibitedView TDS →
Technical60%propylene-glycol-60-technical-gradeView TDS →
USP60%propylene-glycol-60-usp-gradeView TDS →
USP Grade50%50-propylene-glycol-usp-gradeView TDS →
Technical Grade40%40-propylene-glycol-technical-gradeView TDS →
USP Grade40%40-propylene-glycol-usp-gradeView TDS →
20%propylene-glycol-20-inhibitedView TDS →
Technical20%propylene-glycol-20-technical-gradeView TDS →
USP20%propylene-glycol-20-usp-gradeView TDS →
Technical Gradepropylene-glycol-technical-gradeView TDS →

Typical assay shown is the rolling-window mean from the sibling product's most recent lots. Grade selection drives downstream end-use — verify the sibling grade matches your specification before substitution.

Physical & Chemical Properties

PropertySource
外観Thick odorless colorless liquid. Mixes with water. (USCG, 1999)Published reference
FormLiquidPublished reference
Color10 APHA (maximum)Interpreted
臭いPassInterpreted
Specific Gravity (20 °C)between 1.035 and 1.037Interpreted
Density1.04 at 68 °F (USCG, 1999) - Denser than water; will sinkPublished reference
沸点189 deg C maxInterpreted
融点-76 °F (NTP, 1992)Published reference
引火点210 °F (NTP, 1992)Published reference
蒸気圧0.08 mmHg at 68 °F ; 0.13 mmHg at 77 °F (NTP, 1992)Published reference
Solubility (water)greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)Published reference
Refractive Index (nD 20)1.4310 - 1.4330Interpreted

Regulatory & Transport

DOT / 49 CFR

UN Number
Not regulatedAdjudicated
Hazard Class
Not regulatedAdjudicated
Packing Group
Not regulatedAdjudicated
Proper Shipping Name
Not regulatedAdjudicated

GHS / OSHA HazCom 2012

注意喚起語
Not regulatedAdjudicated
H-Codes (Hazard Statements)
Not applicableECHA CLP Annex VI
P-Codes (Precautionary Statements)
Not applicableECHA CLP Annex VI

許容濃度

OSHA PEL (29 CFR 1910.1000)
no canonical
ACGIH TLV
no canonical
NIOSH REL
no canonical
NIOSH IDLH
no canonical

Transport descriptions reflect 49 CFR 172.101 lookup at time of publication. Sourced data: ECHA CLP Annex VI for harmonised classifications, NIOSH Pocket Guide for REL/IDLH, OSHA Z-Tables for PEL. Always verify against the latest regulatory text before shipment-critical decisions.

Supplier Qualification Packet

One zipped download containing the TDS, SDS, latest lot COA (when available), and a fresh Letter of Continuing Guaranty for Propylene Glycol USP Grade. Every file included is SHA-256 hashed and listed in a manifest your QA team can audit.

Download audit packet

Application Guidance

Propylene Glycol USP Grade (USP Grade) is a glycol-based heat-transfer and freeze-protection fluid. Concentration sets the freeze and burst protection; the inhibitor package sets how long the system stays protected from corrosion.

  • Closed-loop heat transfer and process cooling
  • Data-centre and chilled-water freeze protection
  • HVAC hydronic loops and glycol makeup
  • Freeze and burst protection for idle or seasonal systems
  • Humectant and carrier applications (USP/food-grade propylene glycol only)

Verify concentration against the required freeze and burst protection, and confirm elastomer and metallurgy compatibility for the service temperature. Ethylene glycol is toxic by ingestion and must not be used where incidental food or potable contact is possible — specify a propylene glycol grade for those services.

Storage & Handling

Recommended Storage
Cool, dry, well-ventilated area in tightly sealed original containers. Neat glycols are combustible liquids with high flash points (roughly 99–111 °C) and do not require a solvent store; aqueous blends will not sustain combustion. Protect inhibited coolants from contamination and from freezing below their stated protection point.Class-level guidance — not product-specific; the SDS controls.
Handling Precautions
Chemical-resistant gloves and splash goggles. Ethylene glycol grades are toxic by ingestion and must be kept away from food, drink and animals; propylene glycol grades are not. Avoid contact with hot surfaces and hot process equipment. Inhibitor packages deplete in service — monitor rather than top up blindly.Class-level guidance — not product-specific; the SDS controls.
Incompatibilities
Strong oxidizers, strong acids and strong bases. Galvanized (zinc) surfaces are attacked by many inhibited coolant packages. Verify elastomer and gasket compatibility for the service temperature; EPDM is standard for glycol/water service.Class-level guidance — not product-specific; the SDS controls.
Shelf Life
Consult Technical Services for product-specific shelf life

For full hazard, PPE, and emergency response guidance, refer to the Safety Data Sheet (SDS) for this product. The SDS controls in all cases where guidance differs.

Packaging & Logistics

Shipping Description (US DOT)

Not regulated for transport.

Confirm against shipping documents and carrier requirements before tender.

NMFC Class
55

Revision History

Last reviewed 2026-06-17 by Andre Taki, DOT Hazmat Specialist.

VersionDateChangeTrigger
1.12026-06-17Canonical data re-verified: 3 fields updated against independent vendor SDSs, CLP Annex VI, 49 CFR, and OSHA HazCom 2024 (GHS classification, hazard/precautionary codes, signal word, physical properties as applicable).
  • countryOfOrigin· canonical adjudication / reground (coa.data_provenance)
  • dotSubsidiaryHazardClass· canonical adjudication / reground (coa.data_provenance)
  • hsCode· canonical adjudication / reground (coa.data_provenance)
canonical_change
1.02026-05-20Initial URL-first TDS published from canonical chemistry registry.initial

This Technical Data Sheet is provided for technical reference. The Safety Data Sheet (SDS) controls in all cases where guidance differs. Values reflect Alliance Chemical canonical data at time of generation; subsequent revisions are recorded in the Revision History above.

Propylene Glycol USP Grade — Technical Data Sheet | Alliance Chemical