Perchloroethylene ACS Grade

Product Identifier

Perchloroethylene ACS Grade

Grade

ACS Grade

CAS Number

127-18-4

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Synonyms

Tetrachloroethylene; tetrachloroethene; perchloroethylene; PCE; perc

Recommended Use

Industrial solvent and chemical intermediate, only for the uses still permitted under TSCA section 6 (40 CFR Part 751); see Section 15.

Restrictions on Use

After December 8, 2026 this chemical substance (as defined in TSCA section 3(2))/product cannot be distributed in commerce to retailers for any use. After March 8, 2027, this chemical substance (as defined in TSCA section 3(2))/product is and can only be distributed in commerce or processed with a concentration of PCE equal to or greater than 0.1% by weight for the following purposes: (1) Processing as a reactant/intermediate; (2) Processing into formulation, mixture or reaction product; (3) Processing by repackaging; (4) Recycling; (5) Industrial and commercial use as solvent in open-top batch vapor degreasing; (6) Industrial and commercial use as solvent in closed-loop batch vapor degreasing; (7) Industrial and commercial use in maskant for chemical milling; (8) Industrial and commercial use as a processing aid in catalyst regeneration in petrochemical manufacturing; (9) Industrial and commercial use as a processing aid in sectors other than petrochemical manufacturing; (10) Industrial and commercial use as solvent for cold cleaning of tanker vessels; (11) Industrial and commercial use as energized electrical cleaner; (12) Industrial and commercial use in laboratory chemicals; (13) Industrial and commercial use in solvent-based adhesives and sealants; (14) Industrial and commercial use in dry cleaning in 3rd generation machines until December 20, 2027; (15) Industrial and commercial use in all dry cleaning and related spot cleaning until December 19, 2034; (16) Export; and (17) Disposal.

Classification

• Skin corrosion/irritation, Category 2
• Skin sensitization, Category 1
• Serious eye damage/eye irritation, Category 2A
• Specific target organ toxicity, single exposure, Category 3 (narcotic effects)
• Carcinogenicity, Category 1
• Specific target organ toxicity, single exposure, Category 1
• Specific target organ toxicity, repeated exposure, Category 2
• Hazardous to the aquatic environment, long-term hazard, Category 2 †

† GHS environmental hazard class; not adopted under OSHA HCS (29 CFR 1910.1200).

Signal Word

Danger

Hazard Statements

• H315Causes skin irritation
• H317May cause an allergic skin reaction
• H319Causes serious eye irritation
• H336May cause drowsiness or dizziness
• H350May cause cancer
• H370Causes damage to organs
• H373May cause damage to organs through prolonged or repeated exposure
• H411Toxic to aquatic life with long lasting effects

Precautionary Statements

• P201Obtain special instructions before use.
• P202Do not handle until all safety precautions have been read and understood.
• P260Do not breathe dust, fume, gas, mist, vapors or spray.
• P264Wash hands and face thoroughly after handling.
• P270Do not eat, drink or smoke when using this product.
• P272Contaminated work clothing should not be allowed out of the workplace.
• P273Avoid release to the environment.
• P280Wear protective gloves, protective clothing, and eye/face protection.
• P302+P352IF ON SKIN: Wash with plenty of water and soap.
• P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P311IF exposed or concerned: Call a POISON CENTER or doctor.
• P308+P313IF exposed or concerned: Get medical advice or attention.
• P312Call a POISON CENTER or doctor if you feel unwell.
• P314Get medical advice or attention if you feel unwell.
• P321Specific treatment (see first-aid information on this label).
• P332+P313If skin irritation occurs: Get medical advice or attention.
• P333+P313If skin irritation or rash occurs: Get medical advice or attention.
• P337+P313If eye irritation persists: Get medical advice or attention.
• P362Take off contaminated clothing and wash before reuse.
• P391Collect spillage.
• P405Store locked up.
• P501Dispose of contents and container in accordance with local, regional, national, and international regulations.

Classification, hazard (H) and precautionary (P) statements and pictograms per OSHA HCS 2024 (29 CFR 1910.1200, Appendices A–C), aligned with GHS Rev. 7.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.

Skin

Immediately flush with plenty of water for at least 15 minutes while removing contaminated clothing. Wash with soap. Get medical attention immediately.

Inhalation

Move person to fresh air and keep comfortable for breathing. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention immediately.

Ingestion

Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention immediately.

Most Important Symptoms and Effects

• Eye contact causes irritation: redness, pain and tearing.
• Skin contact causes irritation: redness, itching and pain; repeated contact may dry and crack the skin.
• May cause an allergic skin reaction (rash, itching), which can be delayed and recur on later exposure.
• Inhalation of vapors may cause drowsiness, dizziness, headache and nausea.
• A single exposure may damage organs.

Immediate Medical Attention and Special Treatment

• Get immediate medical attention after any significant exposure; symptoms may be delayed.

Suitable Extinguishing Media

Use water spray, alcohol-resistant foam, dry chemical, or CO2. Use measures appropriate to local circumstances.

Unsuitable Extinguishing Media

Do not use a solid water stream as it may scatter and spread fire.

Specific Hazards Arising from the Chemical

Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Hydrogen chloride, chlorine, phosgene and carbon oxides when heated or in a fire.

Personal Precautions

Use PPE as described in Section 8. Ensure adequate ventilation. Evacuate personnel to safe areas.

Environmental Precautions

Prevent leakage or spillage from entering drains, sewers, or waterways.

Containment & Cleanup

Absorb with inert material. Collect in appropriate waste container. Dispose per applicable regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area. Keep away from incompatible materials (see Section 10). Keep containers tightly closed.

Specific Storage Precautions

Keep containers tightly closed in a cool, dry, well-ventilated place, protected from sunlight and moisture. Do not store in aluminum containers. Keep away from strong bases, reactive metals and oxidizers. Store locked up.

Occupational Exposure Limits

Engineering Controls

Use adequate ventilation. Provide eyewash stations and quick-drench showers accessible to areas of use.

Eye/Face Protection

Wear chemical safety goggles or face shield.

Skin Protection

Wear chemical-resistant gloves and protective clothing.

Respiratory Protection

Use a NIOSH-approved air-purifying respirator with cartridges appropriate for the contaminant. For higher exposures or confined spaces, use supplied-air or a powered air-purifying respirator (PAPR).

Exposure limits sourced from NIOSH Pocket Guide, OSHA 29 CFR 1910.1000 and ACGIH TLVs.

Appearance

Colorless, volatile liquid

Odor

Ether-like odor

Odor Threshold

No data available

pH

No data available

Melting Point / Freezing Point

-22 to -19 °C (-8 to -2 °F)

Boiling Point

121 °C (250 °F) at 760 mmHg

Flash Point

No flash point in conventional closed tester.

Evaporation Rate

No data available

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

No data available

Vapor Pressure

13–14 mmHg (1.7–1.8 kPa) at 20 °C

Vapor Density

5.8 (air = 1)

Relative Density

1.62 at 25 °C (water = 1); sinks in water

Solubility

0.15 g/L in water at 20 °C (practically insoluble)

Partition Coefficient (n-octanol/water)

log Kow 2.88

Auto-ignition Temperature

No data available

Decomposition Temperature

No data available

Viscosity

0.89 mPa·s at 20 °C

Particle Characteristics

Not applicable

Form

Liquid

Density

1.619 - 1.626 g/mL

Refractive Index

1.5045 - 1.5065

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Heat, open flame, welding arcs and hot surfaces (vapor decomposes to phosgene and hydrogen chloride); ultraviolet light; moisture.

Incompatible Materials

Strong oxidizers, strong acids and bases, reactive and finely divided metals (aluminum, zinc, alkali metals), amines, peroxides, oxygen.

Hazardous Decomposition Products

Hydrogen chloride, chlorine, phosgene and carbon oxides when heated or in a fire.

See below for route-specific acute toxicity data.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• Eye contact causes irritation: redness, pain and tearing.
• Skin contact causes irritation: redness, itching and pain; repeated contact may dry and crack the skin.
• May cause an allergic skin reaction (rash, itching), which can be delayed and recur on later exposure.
• Inhalation of vapors may cause drowsiness, dizziness, headache and nausea.
• A single exposure may damage organs.

Delayed and Chronic Effects

• Carcinogenicity: may cause or is suspected of causing cancer after long-term exposure (see the carcinogen classification below).
• Prolonged or repeated exposure may damage organs.
• Sensitization: once sensitized, later exposure to very low levels may cause a reaction.
• Repeated skin contact may cause dermatitis (dry, cracked skin).

Carcinogen Classification

Aquatic Hazard

• H411Toxic to aquatic life with long lasting effects

Ecotoxicity

Daphnia EC50: 18 mg/L (48 h, Daphnia magna (static, 22 °C)); Fish LC50: 5 mg/L (96 h, Limanda limanda (dab; range across species 5–8.4 mg/L))

Persistence & Degradability

Persistent — Slow/no aerobic biodegradation (half-life ~180 d aerobic)

Bioaccumulative Potential

log Kow 3.40, BCF 26–115 (measured in fish)

Mobility in Soil

Adsorbs to solids/sediment (measured Koc 200–237)

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

EPA RCRA Waste Codes

U210 (discarded unused product, 40 CFR 261.33(f)); D039 (toxicity characteristic, 0.7 mg/L); F001/F002 (spent halogenated solvent, 40 CFR 261.31)

US DOT (49 CFR)

UN Number

UN1897

Proper Shipping Name

Tetrachloroethylene

Hazard Class

6.1

Packing Group

III

Additional US DOT Requirements

A package containing 100 lb or more of tetrachloroethylene (about 7.4 gal, for example a 55-gal drum) is a hazardous substance: UN1897, Tetrachloroethylene, 6.1, III, RQ (Tetrachloroethylene). Bulk packaging over 119 gal (for example a 275-gal tote): also Marine Pollutant (49 CFR 172.101 Appendix B). Non-bulk packages by highway or rail are excepted from the marine-pollutant requirements (49 CFR 171.4(c)).

Environmental Hazards

Meets GHS aquatic-hazard criteria; may be a marine pollutant under the IMDG Code (vessel transport).

IMDG / IATA classifications may differ from US DOT. Verify current regulations before international shipment.

TSCA Section 6 Restrictions (40 CFR 751)

After December 8, 2026 this chemical substance (as defined in TSCA section 3(2))/product cannot be distributed in commerce to retailers for any use. After March 8, 2027, this chemical substance (as defined in TSCA section 3(2))/product is and can only be distributed in commerce or processed with a concentration of PCE equal to or greater than 0.1% by weight for the following purposes: (1) Processing as a reactant/intermediate; (2) Processing into formulation, mixture or reaction product; (3) Processing by repackaging; (4) Recycling; (5) Industrial and commercial use as solvent in open-top batch vapor degreasing; (6) Industrial and commercial use as solvent in closed-loop batch vapor degreasing; (7) Industrial and commercial use in maskant for chemical milling; (8) Industrial and commercial use as a processing aid in catalyst regeneration in petrochemical manufacturing; (9) Industrial and commercial use as a processing aid in sectors other than petrochemical manufacturing; (10) Industrial and commercial use as solvent for cold cleaning of tanker vessels; (11) Industrial and commercial use as energized electrical cleaner; (12) Industrial and commercial use in laboratory chemicals; (13) Industrial and commercial use in solvent-based adhesives and sealants; (14) Industrial and commercial use in dry cleaning in 3rd generation machines until December 20, 2027; (15) Industrial and commercial use in all dry cleaning and related spot cleaning until December 19, 2034; (16) Export; and (17) Disposal.

CERCLA Reportable Quantity (RQ)

Tetrachloroethylene (CAS 127-18-4) 100 lb (45.4 kg), about 7.4 US gal of product.

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-10-02; US EPA TSCA Active Inventory 2026-10-02; EPCRA SARA 313 (TRI) 2026-10-02.

Revision Date

2026-10-13

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.