Industrial chemicals · Taylor, TXTechnical Data Sheet
Technical Data Sheet
Isopropyl Acetate 99.98% ACS Grade
ACS Grade · 99.98%
- CAS number
- 108-21-4
- UN number
- UN1220
- Hazard class · packing group
- 3 · PG II
- Structure
Structure · PubChem - Grade
- ACS Grade · 99.98%
- Signal word
- Danger
- Hazards
- Proper shipping name
- Isopropyl acetate
Last reviewed 2026-07-17 by Andre Taki, Chief Commercial Officer.
Identity & Composition
- Product Name
- Isopropyl Acetate 99.98% ACS Grade
- Alliance Code
- isopropyl-acetate-99-98-acs-grade
- Grade
- ACS Grade
- Concentration
- 99.98%
- CAS Number
- 108-21-4PubChem
- Formula
- —PubChem
- Molecular Weight
- 102.13PubChem
- Product Type
- Solution
- IUPAC Name
- propan-2-yl acetatePubChem
- InChI-Key
- JMMWKBVZLWUJPJ-UHFFFAOYSA-NPubChem
- SMILES
- CC(C)OC(=O)CPubChem
Pharmacopoeia Compliance:ACS
Specifications
| Test | Specification | Typical | Method | Source |
|---|---|---|---|---|
| Assay (isopropyl acetate) | 99.5 % min. | 99.88 % | GC | Interpreted |
| Acidity (as acetic acid) | 0.005 wt % max. | 0.00078 wt % | — | Interpreted |
| Color (Pt-Co) | 5 max. | 2 | — | Interpreted |
| Copper (Cu) | 0.02 ppm max. | 0.0018 ppm | — | Interpreted |
| Identification | Conforms | Passes test | FTIR | Interpreted |
| Iron (Fe) | 0.1 ppm max. | 0.017 ppm | — | Interpreted |
| Nickel (Ni) | 0.02 ppm max. | 0.0014 ppm | — | Interpreted |
| Lead (Pb) | 0.1 ppm max. | 0.0039 ppm | — | Interpreted |
| Non-volatile matter | 0.002 % max. | 0.00026 % | — | Interpreted |
| Water | 0.05 % max. | 0.012 % | Karl Fischer | Interpreted |
| Isopropanol (free alcohol) | 0.1 % max. | 0.007 % | GC-FID (ASTM D3545) | Interpreted |
| Substances darkened by sulfuric acid | Passes test | Passes test | ACS reagent method | Interpreted |
| Distillation range (760 mm Hg) | 87 - 90 °C | 88.5 °C | ASTM D1078 | Interpreted |
Values are reproduced from the current product reference. Source labels do not by themselves establish a supplier guarantee or a test result for your lot. Confirm applicable acceptance limits and request lot-specific documentation.
Available GradesSame CAS, alternate grades and concentrations
| Grade | Concentration | Typical Assay | SKU | TDS |
|---|---|---|---|---|
| This grade ACS Grade | 99.98% | — | current | current |
| Technical | 99.98% | — | isopropyl-acetate-99-98 | View TDS → |
Typical assay shown is the rolling-window mean from the sibling product's most recent lots. Grade selection drives downstream end-use — verify the sibling grade matches your specification before substitution.
Physical & Chemical Properties
| Property | Value | Source |
|---|---|---|
| Appearance | Colorless, volatile liquid | Adjudicated |
| Form | Liquid | Published reference |
| Odor | Sweet, fruity ester odor | Adjudicated |
| Specific Gravity | 0.872 at 20 °C (water = 1) | Adjudicated |
| Density | 0.874 at 68 °F (USCG, 1999) - Less dense than water; will float | Published reference |
| Boiling Point | 89 °C (192 °F) | Adjudicated |
| Melting Point | -73 °C (-100 °F) | Adjudicated |
| Flash Point | 2–5 °C (36–41 °F), closed cup | Adjudicated |
| Vapor Pressure | About 48 mmHg (6.5 kPa) at 20–21 °C | Adjudicated |
| Vapor Density | 3.5 (air = 1) | Adjudicated |
| Solubility (water) | Slightly soluble in water (about 31 g/L at 20 °C); miscible with most organic solvents | Adjudicated |
| Refractive Index (nD 20) | 1.376 - 1.378 | Interpreted |
| Viscosity | About 0.5 mPa·s at 25 °C | Adjudicated |
Polar solvent — purity vs. intended end-use (electronics, pharma, general industrial) is the dominant grade consideration. See application guidance for grade selection.
Materials of ConstructionService envelope ≈ 99.98%
| Material | Rating | Max T (°C) | Notes | Source |
|---|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. | Parker O-ring Chemical Compatibility |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters | Cole-Parmer Chemical Compatibility |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. | Parker O-ring Chemical Compatibility |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing | Cole-Parmer Chemical Compatibility |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. | Cole-Parmer Chemical Compatibility |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. | Cole-Parmer Chemical Compatibility |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. | Cole-Parmer Chemical Compatibility |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact | Cole-Parmer Chemical Compatibility |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. | Cole-Parmer Chemical Compatibility |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. | Cole-Parmer Chemical Compatibility |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters | Cole-Parmer Chemical Compatibility |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters | Cole-Parmer Chemical Compatibility |
Ratings reflect the service envelope (concentration × temperature) shown. Always confirm against your specific duty cycle and contact-time before equipment selection. The most cautious rating across overlapping references is shown.
Materials Selection Tool
Showing 12 of 12 material ratings within the selected envelope.
| Material | Rating | Max T (°C) | Notes |
|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters |
Regulatory & Transport
DOT / 49 CFR
- UN Number
- UN122049 CFR 172.101
- Hazard Class
- 3Adjudicated
- Packing Group
- IIAdjudicated
- Proper Shipping Name
- Isopropyl acetateAdjudicated
GHS / OSHA HCS 2024
- Signal Word
- DangerAdjudicated
- H-Codes (Hazard Statements)
- H225, H319, H336Adjudicated
- P-Codes (Precautionary Statements)
- P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, P501Adjudicated
Occupational Exposure Limits
- OSHA PEL (29 CFR 1910.1000)
- 250 ppm TWAOSHA 29 CFR 1910.1000
- ACGIH TLV
- 100 ppm TWA / 200 ppm STELAdjudicated
- NIOSH REL
- —no canonical
- NIOSH IDLH
- 1,800 ppmAdjudicated
Regional Classifications
- EC Number (EU EINECS)
- 203-561-1Web SDS consensus
- REACH SVHC
- Not listedWeb SDS consensus
- California Prop 65
- Not listedWeb SDS consensus
- WGK Water Hazard (DE)
- 1Web SDS consensus
- TDG Classification (Canada)
- un1220, class 3, pg iiWeb SDS consensus
Transport descriptions reflect 49 CFR 172.101 lookup at time of publication. Sourced data: NIOSH Pocket Guide for REL/IDLH, OSHA Z-Tables for PEL. Always verify against the latest regulatory text before shipment-critical decisions.
Health & Fire Hazard
NFPA 704
- Health:1Web SDS consensus
- Fire:3Web SDS consensus
- Reactivity:0Web SDS consensus
- Specific: —
HMIS III
Health1Web SDS consensus
Flammability3Web SDS consensus
Physical Hazard0Web SDS consensus
PPEBWeb SDS consensus
Acute Toxicology
- LD₅₀ Oral (rat)
- 3,000–6,750 mg/kg (rat)Adjudicated
- LD₅₀ Dermal (rabbit)
- > 17,400 mg/kgAdjudicated
- LC₅₀ Inhalation (rat, 4 h)
- 50.6 mg/L (rat, 8 h)Adjudicated
NFPA 704 ratings 0 (no hazard) – 4 (severe hazard) per NFPA 704 standard. HMIS III ratings 0 – 4 per the American Coatings Association. Acute toxicology values from SDS Section 11 or NIOSH RTECS.
Supplier Qualification Packet
One zipped download containing the TDS, SDS, latest lot COA (when available), and a fresh Letter of Continuing Guaranty for Isopropyl Acetate 99.98% ACS Grade. Every file included is SHA-256 hashed and listed in a manifest your QA team can audit.
Catalog EquivalentsCross-reference vs major chemical suppliers
Sigma-Aldrich
| SKU | Grade | Conc. | Match | Notes |
|---|---|---|---|---|
| 109584 | ACS reagent | ≥99.5% | Unverified candidate | Same ACS reagent grade. |
Cross-references are informational. Confirm against the manufacturer's current specification before substitution. Competitor trademarks are property of their respective owners.
Applications
- General-purpose fast-evaporating solvent, miscible with most common organic solvents, with properties between ethyl and butyl acetatestobec.com
- Active solvent for synthetic resins including cellulose acetate butyrate, nitrocellulose, vinyl copolymers, polyesters, polyamides, acrylics and alkydsstobec.com
- Solvent in coatings: automotive OEM and refinish, can and coil, general industrial, industrial maintenance and marine, industrial wood, transportationstobec.com
- Fragrance carrier in cosmetics and personal care, and solvent in flexographic and gravure printing inksstobec.com
- Solvent for cellulose, plastics, oils and fats; component of some printing inks and perfumescorecheminc.com
Applications are drawn from published manufacturer and supplier documentation; each is sourced. Suitability for a specific use is the buyer's to confirm.
Storage & Handling
- Recommended Storage
- Keep tightly closed in a cool, well-ventilated flammables area away from ignition sources, oxidizers, acids and bases. Store locked up. Ground and bond containers.Adjudicated
- Handling Precautions
- Use chemical-resistant gloves and splash goggles. Bond and ground during transfer to prevent static accumulation. Eliminate ignition sources within vapor envelope.Class-level guidance — not product-specific; the SDS controls.
- Incompatibilities
- Strong oxidizing agents; strong acids and bases (hydrolysis).Adjudicated
- Shelf Life
- Consult Technical Services for product-specific shelf life
For full hazard, PPE, and emergency response guidance, refer to the Safety Data Sheet (SDS) for this product. The SDS controls in all cases where guidance differs.
Packaging & Logistics
Shipping Description (US DOT)
UN1220, Isopropyl acetate, 3, PG II
Sourced from 49 CFR 172.101. Confirm against shipping documents and carrier requirements before tender.
NMFC Class
70
Placard
Flammable Liquid
Packing Group
PG II
Revision History
Last reviewed 2026-07-17 by Andre Taki, Chief Commercial Officer, DOT Hazmat–certified (49 CFR 172.704).
| Version | Date | Change | Trigger |
|---|---|---|---|
| 1.7 | 2026-10-08 | Canonical data updated: 23 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.6 | 2026-10-07 | Canonical data updated: 3 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.5 | 2026-10-05 | Canonical data updated: 2 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.4 | 2026-09-30 | Canonical data updated: 4 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.3 | 2026-08-05 | Canonical data updated: 3 fields changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.2 | 2026-07-22 | Canonical data updated: 1 field changed via the provenance/adjudication pipeline.
| canonical_change |
| 1.1 | 2026-07-17 | Canonical data re-verified: 25 fields updated against independent vendor SDSs, CLP Annex VI, 49 CFR, and OSHA HazCom 2024 (GHS classification, hazard/precautionary codes, signal word, physical properties as applicable).
| canonical_change |
| 1.0 | 2026-05-20 | Initial URL-first TDS published from canonical chemistry registry. | initial |
This Technical Data Sheet is provided for technical reference. The Safety Data Sheet (SDS) controls in all cases where guidance differs. Values reflect Alliance Chemical canonical data at time of generation; subsequent revisions are recorded in the Revision History above.