Industrial chemicals · Taylor, TXTechnical Data Sheet
Propylene Glycol USP Grade
USP Grade
Identity & Composition
- Product Name
- Propylene Glycol USP Grade
- Alliance Code
- propylene-glycol-usp-grade
- Grade
- USP Grade
- Concentration
- —
- CAS Number
- 57-55-6PubChem
- Formula
- C3H8O2PubChem
- Molecular Weight
- 76.09PubChem
- Product Type
- pure_substance
Specifications
| Test | Specification | Typical | Method | Source |
|---|---|---|---|---|
| Assay (C3H8O2) | not less than 99.5 percent | 99.9 % | GC, thermal conductivity detector, 1-m x 4-mm column packed with 5% G16 on support S5, area normalization excluding air and water | USP monograph |
| Acidity | not more than 0.20 mL of 0.10 N sodium hydroxide is required | 0.04 | Titration of 10 mL with 0.10 N sodium hydroxide to phenolphthalein endpoint | USP monograph |
| Chloride | 0.007% | 0.00003 % | USP <221> | USP monograph |
| Heavy metals | 5 ppm | 0.5 ppm | USP <231> | USP monograph |
| Identification A (Infrared Absorption) | Infrared Absorption 〈197F〉 on undried specimen | Passes test | USP <197F> | USP monograph |
| Iron | 0.50 weight ppm (maximum) | 0.05 ppm | HOC 0290 | Supplier specification |
| Limit of Diethylene Glycol | NMT 0.10% | 0.003% | GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standard | USP monograph |
| Limit of Ethylene Glycol | NMT 0.10% | 0.002% | GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standard | USP monograph |
| Residual solvents | Pass | Passes test | USP <467> | Supplier specification |
| Residue on ignition | 0.0070 wt% max (3.5 mg from 50 g) | 0.0005 wt% | Ignition of 50 g, residue moistened with 0.5 mL sulfuric acid and ignited to constant weight | USP monograph |
| Sulfate | 0.006% | 0.0005 % | USP <221> | USP monograph |
| Suspended matter | Pass | Passes test | HOC 0171 | Supplier specification |
| Water | not more than 0.2% | 0.03 % | USP <921> Method I (Karl Fischer) | USP monograph |
| Elemental impurities | Meets USP <232> / ICH Q3D oral limits | Passes test | USP <232> / <233>, ICP-MS | Interpreted |
| Microbial enumeration | TAMC ≤ 100 CFU/g; TYMC ≤ 10 CFU/g | Passes test | USP <61> | Interpreted |
| arsenic | 1 ppm max | 0.02 ppm | — | Supplier specification |
| dp | 189 Deg.C max | 188.2 °C | — | Supplier specification |
| dpg | 0.1 %m/m max | 0.03 %m/m | — | Supplier specification |
| ibp | 185 Deg.C min | 186.8 °C | — | Supplier specification |
| pb | 1 mg/kg max | 0.01 ppm | — | Supplier specification |
| meg | 0.001 %m/m max | 0.0005 %m/m | — | Supplier specification |
| oxidizing substances | 0.2 ml max | 0.03 | — | Supplier specification |
| po | 0.001 %m/m max | 0.0002 %m/m | — | Supplier specification |
| tpg | 0.03 %m/m max | 0.006 %m/m | — | Supplier specification |
Specification values are guaranteed limits. Typical values are representative of production lots and are not guaranteed. Lot-specific certificates of analysis ship with every order.
Available GradesSame CAS, alternate grades and concentrations
| Grade | Concentration | Typical Assay | SKU | TDS |
|---|---|---|---|---|
| This grade USP Grade | — | — | current | current |
| — | 60% | — | propylene-glycol-60-inhibited | View TDS → |
| Technical | 60% | — | propylene-glycol-60-technical-grade | View TDS → |
| USP | 60% | — | propylene-glycol-60-usp-grade | View TDS → |
| USP Grade | 50% | — | 50-propylene-glycol-usp-grade | View TDS → |
| Technical Grade | 40% | — | 40-propylene-glycol-technical-grade | View TDS → |
| USP Grade | 40% | — | 40-propylene-glycol-usp-grade | View TDS → |
| — | 20% | — | propylene-glycol-20-inhibited | View TDS → |
| Technical | 20% | — | propylene-glycol-20-technical-grade | View TDS → |
| USP | 20% | — | propylene-glycol-20-usp-grade | View TDS → |
| Technical Grade | — | — | propylene-glycol-technical-grade | View TDS → |
Typical assay shown is the rolling-window mean from the sibling product's most recent lots. Grade selection drives downstream end-use — verify the sibling grade matches your specification before substitution.
Physical & Chemical Properties
| Property | Value | Source |
|---|---|---|
| Appearance | Thick odorless colorless liquid. Mixes with water. (USCG, 1999) | Published reference |
| Form | Liquid | Published reference |
| Color | 10 APHA (maximum) | Supplier specification |
| Odor | Pass | Supplier specification |
| Specific Gravity (20 °C) | between 1.035 and 1.037 | USP monograph |
| Density | 1.04 at 68 °F (USCG, 1999) - Denser than water; will sink | Published reference |
| Boiling Point | 189 deg C max | Supplier specification |
| Melting Point | -76 °F (NTP, 1992) | Published reference |
| Flash Point | 210 °F (NTP, 1992) | Published reference |
| Vapor Pressure | 0.08 mmHg at 68 °F ; 0.13 mmHg at 77 °F (NTP, 1992) | Published reference |
| Solubility (water) | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) | Published reference |
| Refractive Index (nD 20) | 1.4310 - 1.4330 | Supplier specification |
Polar solvent — purity vs. intended end-use (electronics, pharma, general industrial) is the dominant grade consideration. See application guidance for grade selection.
Materials of Construction
| Material | Rating | Max T (°C) | Notes | Source |
|---|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. | Parker O-ring Chemical Compatibility |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters | Cole-Parmer Chemical Compatibility |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. | Parker O-ring Chemical Compatibility |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing | Cole-Parmer Chemical Compatibility |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. | Cole-Parmer Chemical Compatibility |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. | Cole-Parmer Chemical Compatibility |
Glass (borosilicate) glass ceramic | Excellent | 100 | Inert | Cole-Parmer Chemical Compatibility |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. | Cole-Parmer Chemical Compatibility |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact | Cole-Parmer Chemical Compatibility |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. | Cole-Parmer Chemical Compatibility |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. | Cole-Parmer Chemical Compatibility |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters | Cole-Parmer Chemical Compatibility |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters | Cole-Parmer Chemical Compatibility |
Ratings reflect the service envelope (concentration × temperature) shown. Always confirm against your specific duty cycle and contact-time before equipment selection. The most cautious rating across overlapping references is shown.
Materials Selection Tool
Showing 13 of 13 materials compatible at the selected envelope.
| Material | Rating | Max T (°C) | Notes |
|---|---|---|---|
Buna-N (NBR) elastomer | Fair | 60 | Acceptable for alcohols; poor for ketones. |
EPDM elastomer | Fair | — | Good for alcohols, poor for esters |
Viton (FKM) elastomer | Fair | 80 | Swells in acetone and esters; avoid for those. |
FFKM (Kalrez) fluoropolymer | Excellent | 200 | Premium ester / ketone sealing |
PTFE fluoropolymer | Excellent | 200 | Universal solvent compatibility. |
Borosilicate Glass glass ceramic | Excellent | 100 | Universally inert. |
Glass (borosilicate) glass ceramic | Excellent | 100 | Inert |
316L Stainless Steel metal | Excellent | 80 | Inert; preferred for high-purity solvent service. |
Aluminium metal | Good | 40 | Acceptable; avoid prolonged wet contact |
Carbon Steel metal | Fair | 50 | Trace moisture causes rust; flash-rust prevention required. |
HDPE thermoplastic | Fair | 40 | Swells with many polar solvents; verify per solvent. |
PP thermoplastic | Good | 50 | Acceptable but watch swelling with esters |
PVC thermoplastic | Fair | 25 | Esters soften PVC; avoid for esters |
Regulatory & Transport
DOT / 49 CFR
- UN Number
- Not regulatedAdjudicated
- Hazard Class
- Not regulatedAdjudicated
- Packing Group
- Not regulatedAdjudicated
- Proper Shipping Name
- Not regulatedAdjudicated
GHS / OSHA HazCom 2012
- Signal Word
- Not regulatedAdjudicated
- H-Codes (Hazard Statements)
- Not applicableECHA CLP Annex VI
- P-Codes (Precautionary Statements)
- Not applicableECHA CLP Annex VI
Occupational Exposure Limits
- OSHA PEL (29 CFR 1910.1000)
- —no canonical
- ACGIH TLV
- —no canonical
- NIOSH REL
- —no canonical
- NIOSH IDLH
- —no canonical
Transport descriptions reflect 49 CFR 172.101 lookup at time of publication. Sourced data: ECHA CLP Annex VI for harmonised classifications, NIOSH Pocket Guide for REL/IDLH, OSHA Z-Tables for PEL. Always verify against the latest regulatory text before shipment-critical decisions.
Supplier Qualification Packet
One zipped download containing the TDS, SDS, latest lot COA (when available), and a fresh Letter of Continuing Guaranty for Propylene Glycol USP Grade. Every file included is SHA-256 hashed and listed in a manifest your QA team can audit.
Application Guidance
Propylene Glycol USP Grade (USP Grade) is a polar solvent. Grade selection (technical, ACS, electronics, USP) determines acceptable residue and impurity levels for the intended end-use.
- Cleaning and degreasing (technical-grade)
- Coatings, inks, and adhesives formulation
- Reaction solvent for chemical synthesis
- Pharmaceutical manufacturing (USP-grade)
- Electronics-grade cleaning and rinse applications
Flammable. Bond and ground equipment during transfer. Verify grade matches end-use specification before substitution.
Storage & Handling
- Recommended Storage
- Cool, well-ventilated flammable-liquid storage area. Tightly sealed original containers. Segregate from oxidizers and acids. Bond and ground bulk storage.Class-level guidance — not product-specific; the SDS controls.
- Handling Precautions
- Use chemical-resistant gloves and splash goggles. Bond and ground during transfer to prevent static accumulation. Eliminate ignition sources within vapor envelope.Class-level guidance — not product-specific; the SDS controls.
- Incompatibilities
- Strong oxidizers, strong acids, isocyanates, anhydrides. Hygroscopic — protect from atmospheric moisture for water-sensitive end uses.Class-level guidance — not product-specific; the SDS controls.
- Shelf Life
- Consult Technical Services for product-specific shelf life
For full hazard, PPE, and emergency response guidance, refer to the Safety Data Sheet (SDS) for this product. The SDS controls in all cases where guidance differs.
Packaging & Logistics
Shipping Description (US DOT)
Not regulated for transport.
Confirm against shipping documents and carrier requirements before tender.
Revision History
Last reviewed 2026-06-17 by Andre Taki, DOT Hazmat Specialist.
| Version | Date | Change | Trigger |
|---|---|---|---|
| 1.1 | 2026-06-17 | Canonical data re-verified: 3 fields updated against independent vendor SDSs, CLP Annex VI, 49 CFR, and OSHA HazCom 2024 (GHS classification, hazard/precautionary codes, signal word, physical properties as applicable).
| canonical_change |
| 1.0 | 2026-05-20 | Initial URL-first TDS published from canonical chemistry registry. | initial |
This Technical Data Sheet is provided for technical reference. The Safety Data Sheet (SDS) controls in all cases where guidance differs. Values reflect Alliance Chemical canonical data at time of generation; subsequent revisions are recorded in the Revision History above.